Calcium signalling
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Calcium signalling a practical approach

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Published by Oxford University Press in Oxford, New York .
Written in English

Subjects:

  • Calcium -- Physiological effect -- Research -- Methodology,
  • Calcium -- Analysis,
  • Second messengers (Biochemistry) -- Research -- Methodology,
  • Cellular signal transduction -- Research -- Methodology

Book details:

Edition Notes

Other titlesCellular calcium.
Statementedited by Alexei Tepikin.
SeriesThe practical approach series, Practical approach series
ContributionsTepikin, Alexei.
Classifications
LC ClassificationsQP535.C2 C46 2001
The Physical Object
Paginationxix, 230 p., 10 p. of plates :
Number of Pages230
ID Numbers
Open LibraryOL21747348M
ISBN 100199638489, 0199638470
LC Control Number00060683
OCLC/WorldCa44678630

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Calcium Signalling in Cancer: Medicine & Health Science Books @ Skip to main content. Try Prime Hello, Sign in Account & Lists Sign in Account & Lists Returns & Orders Try Prime Cart. Books. Go Search Hello Select your address Cited by: 8. Comprehensive and cutting-edge, Calcium Signalling: Methods and Protocols is a valuable resource that covers both conceptual and methodological viewpoints to aid beginners and experts in furthering their studies in the developing field of calcium homeostasis research. The first edition of James Putney’s Calcium Signaling offered readers a comprehensive view of the fascinating diversity of technologies that the new field of calcium signaling employed. And while that work is still regarded as a premier text on the basics of calcium signaling, progress has been so dramatic that an update is now required. The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition.

In Calcium Signaling Protocols, David Lambert and a panel of leading authorities present a wide range of experimental protocols for studying Ca2+ signaling. These optimized techniques cover the more common applications, including 45Ca2+ flux measurements, and basic fluorometric technology, as well as more sophisticated methods, including confocal microscopy and . The process of calcium signaling comprises a series of molecular and biophysical events that link an external stimulus to the expression of some appropriate intracellular response through an increase in cytoplasmic Ca2+ as a signal. The external signal is most commonly a neurotransmitter, hormone or growth factor; but in the case of excitable cells, the initial . Calcium ions (Ca2+) impact nearly every aspect of cellular life. This review examines the principles of Ca2+ signaling, from changes in protein conformations driven by Ca2+ to the mechanisms that control Ca2+ levels in the cytoplasm and organelles. Also discussed is the highly localized nature of Ca2+-mediated signal transduction and its specific roles in . Calmodulin and Signal Transduction focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory .

The first cellular type affected by SCA2 degeneration is the Purkinje neurons in the cerebellum. It has been postulated that SCA begins when calcium signaling pathways are disrupted in cerebellar Purkinje cells either as a result of an excitotoxic increase or a compensatory suppression of calcium signaling (Kasumu and Bezprozvanny, ).   Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and by: 8.   The first edition of James Putney's Calcium Signaling offered readers a comprehensive view of the fascinating diversity of technologies that the new field of calcium signaling employed. And while that work is still regarded as a premier text on the basics of calcium signaling, progress has been so dramatic that an update is now Edition: 2nd Edition. Calcium (Ca2+) functions as a universal messenger in eukaryotes and regulates many intracellular processes such as cell division and gene expression. However, the physiological role of Ca2+ in prokaryotic cells remains unclear. Indirect evidence suggests that Ca2+ is involved in a wide variety of bacterial cellular processes including membrane transport mechanisms Cited by: 1.